Indications and contraindications for living kidney donations

Kidney t ransplant is the best t reatment opt ion for end-stage kidney failure. The main barriers to this therapy are scarcit y of cadaveric donors and the comorbidit ies of the pat ients with end-stage kidney failure, which prevent the t ransplant . Living kidney donor t ransplant makes it possible to ease the lack of cadaveric-donor organs and also presents bet ter results than cadaveric t ransplants. The principal indicat ion for living kidney donor t ransplant is pre-empt ive t ransplant . This w ill allow the pat ient to avoid the complicat ions of dialysis and it has also been demonstrat ed that it has bet ter results than t ransplants carried out af ter dialysis has been init iated. Priorit y indicat ions of living donor t ransplant are also monozygot ic tw ins and HLA ident ical siblings. There are also very favourable condit ions for young, male donor candidates. However, living donor t ransplants have worse results if the donor is over 60-65 years and the recipient is young, this possibly being a relat ive contraindicat ion. There is an absolute cont raindicat ion for living donat ion when the recipient has diseases with a high risk of aggressive relapse in the graf ts: Focal and segmental hyalinosis that have had early relapse in the f irst t ransplant . Atypical haemolyt ic uraemic syndrome due to def icit or malfunct ion of the complement regulatory proteins. Early development of glomerulonephrit is due to ant i-glomerular basement membrane ant ibodies in pat ients w ith Alport ’s syndrome. Primary hyperoxaluria. Indicaciones y contraindicaciones de la donación renal de vivo